Author

H. Isaksson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Biochemistry· 1 Biophysics· 1 Evolutionary Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Assay:imaging· 4 Organism:rat· 3 Approach:statistical model· 2 Organism:Arabidopsis· 1 Research Focus:benchmarking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

E. Libby· 2 shared M. Guizar-Sicairos· 2 shared M. Hammerman· 2 shared P. Eliasson· 2 shared A. Brännström· 1 shared A. Edthofer· 1 shared A. Gustafsson· 1 shared A. Sandberg· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersEvolutionary Biology

E. Libby

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Multi-modal Phantom Experiments, mimicking Flow through the Mitral Heart Valve

L. Christierson, P. Frieberg, T. Lala, J. Toger, P. Liuba, J. Revstedt, H. Isaksson, N. Hakacova

This study creates a multi-modal benchmark dataset for FSI models using an in vitro phantom setup to mimic flow through the mitral heart valve, providing validation data for computational models.

bioRxiv · Feb 20, 2024 · PreprintBioengineering

Minor variations in multicellular life cycles have major effects on adaptation

H. Isaksson, A. Brännström, E. Libby

The paper shows that small differences in multicellular life cycles significantly affect adaptation through distinct mutation dynamics.

bioRxiv · Nov 2, 2022Evolutionary Biology

Overexpression of the plastidal pseudo-protease AtFtsHi3 confers drought tolerance without penalizing growth

S. D. Cook, L. S. Mishra, H. Isaksson, I. R. Straub, M. Abele, S. Mishra, C. Ludwig, E. Libby, C. Funk

This study shows overexpression of AtFtsHi3 in Arabidopsis improves drought tolerance without affecting growth by altering stomatal density and enhancing water use efficiency.

bioRxiv · Oct 17, 2022 · PreprintBiochemistry

Heterotopic ossification in intact rat Achilles tendons is characterized by unique mineralized collagen fiber structures

M. Pierantoni, M. Hammerman, L. Andersson, I. S. Barreto, V. Novak, H. Isaksson, P. Eliasson

This study characterizes heterotopic ossification in rat Achilles tendons using synchrotron X-ray tomography, revealing unique mineralized collagen fiber structures and their growth dynamics.

bioRxiv · Jun 28, 2022 · PreprintPhysiology

A musculoskeletal finite element model of rat knee joint for evaluating cartilage biomechanics during gait

G. A. Orozco, K. Karjalainen, E. K. Moo, L. Stenroth, P. Tanska, J. L. Rios, T. V. Tuomainen, M. J. Nissi, H. Isaksson, W. Herzog, R. K. Korhonen

This paper develops a musculoskeletal finite element model of a rat knee joint to study cartilage biomechanics during gait, revealing compartment-specific stress and strain patterns.

bioRxiv · Sep 1, 2021Bioengineering

3D printed lung on a chip device with a stretchable nanofibrous membrane for modeling ventilator induced lung injury

S. Tas, E. Rehnberg, D. A. Bölükbas, J. P. Beech, L. Nasi Kazado, I. Svenningsson, M. Arvidsson, A. Sandberg, K. A. Dahlgren, A. Edthofer, A. Gustafsson, H. Isaksson, J. A. Wood, J. O. Tegenfeldt, D. E. Wagner

This paper develops a 3D printed lung-on-a-chip device with a stretchable nanofibrous membrane to model ventilator-induced lung injury by mimicking mechanical stretch and air-liquid interface conditions.

bioRxiv · Jul 2, 2021 · PreprintBioengineering

Mineral crystal thickness in calcified cartilage and subchondral bone in healthy and osteoarthritic knees

M. A. J. Finnilä, S. Das Gupta, M. J. Turunen, I. Kestilä, A. Turkiewicz, V. Lutz-Bueno, E. Folkesson, M. Holler, N. Ali, V. Hughes, H. Isaksson, J. Tjörnstrand, P. Önnerfjord, M. Guizar-Sicairos, S. Saarakkala, M. Englund

The paper measures mineral crystal thickness in calcified cartilage and subchondral bone of healthy and osteoarthritic knees, finding increased thickness in the unloaded lateral compartment and decreased thickness in subchondral bone with OA severity.

bioRxiv · Jun 15, 2021 · PreprintBiophysics

Diminishing effects of mechanical loading over time during rat Achilles tendon healing

H. Khayyeri, M. Hammerman, M. Turunen, P. Blomgran, T. Notermans, M. Guizar-Sicairos, P. Eliasson, H. Isaksson

This study examines how different loading magnitudes affect Achilles tendon healing in rats, finding early benefits of loading that diminish by 4 weeks.

bioRxiv · Jul 14, 2020Bioengineering