Author

P. Purhonen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

H. Hebert· 3 shared C. Jegerschöld· 1 shared C. Kang· 1 shared E. Lee· 1 shared G. D. Mawla· 1 shared J.-J. Song· 1 shared K. Bouazoune· 1 shared L. Cao· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiochemistry

H. Hebert

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3 papers

Recent·Most cited

The membrane-cytoplasmic linker defines activity of FtsH proteases in Pseudomonas aeruginosa clone C

G. D. Mawla, S. M. Kamal, L. Cao, P. Purhonen, H. Hebert, R. T. Sauer, T. A. Baker, U. Romling

This study shows that the MC linker in PaFtsH2 affects its substrate processing efficiency, and modifying it can enhance its function in Pseudomonas aeruginosa.

bioRxiv · Jun 19, 2023 · PreprintBiochemistry

CHD7 interacts with the nucleosome acidic patch for its efficient activity via its N-terminal region

E. Lee, C. Kang, P. Purhonen, H. Hebert, K. Bouazoune, S. Hohng, J.-J. Song

This study identifies the N-terminal region of CHD7 as critical for its ATPase activity and nucleosome remodeling through interactions with the nucleosome acidic patch.

bioRxiv · Nov 19, 2020 · PreprintBiochemistry

Arachidonic acid promotes the binding of 5-lipoxygenase on nanodiscs containing 5-lipoxygenase activating protein in the absence of calcium-ions.

R. B. Kumar, P. Purhonen, H. Hebert, C. Jegerschöld

The paper investigates whether arachidonic acid (AA) enables 5-lipoxygenase (5LO) binding to FLAP-containing nanodiscs without calcium ions, finding that AA promotes complex formation independently of calcium.

bioRxiv · Jan 22, 2020Biochemistry