CHD7 interacts with the nucleosome acidic patch for its efficient activity via its N-terminal region
E. Lee, C. Kang, P. Purhonen, H. Hebert, K. Bouazoune, S. Hohng, J.-J. Song
This study identifies the N-terminal region of CHD7 as critical for its ATPase activity and nucleosome remodeling through interactions with the nucleosome acidic patch.
bioRxiv · Nov 19, 2020 · PreprintBiochemistry