BiochemistryeLifePeer-reviewed
SDR enzymes oxidize specific lipidic alkynylcarbinols into cytotoxic protein-reactive species
P. Demange, E. Joly, J. Marcoux…·S. Britton
The paper identifies SDR enzymes as bioactivators of lipidic alkynylcarbinols, converting them into cytotoxic electrophiles that modify proteins and induce cell death.
DOI 10.7554/elife.73913