Author

P. Demange

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:E. coli· 1 Assay:proteomics· 1

Frequent Co-Authors

A. E. Taylor· 1 shared A. Fraser· 1 shared B. Elias· 1 shared B. I. Iorga· 1 shared C. Barthes· 1 shared C. Gutierrez· 1 shared C. Laguri· 1 shared C. Noirot· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperEvolutionary Biology

A. E. Taylor

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mycobacterial resistance to zinc poisoning requires assembly of P-ATPase-containing membrane metal efflux platforms

Y.-M. Boudehen, M. Faucher, X. Marechal, R. Miras, J. Rech, O. Seneque, M. Wallat, P. Demange, J.-Y. Bouet, O. Saurel, P. Catty, C. Gutierrez, O. Neyrolles

The paper identifies PacL1 as a scaffold that assembles P-ATPase-containing metal efflux platforms in Mycobacterium tuberculosis, contributing to zinc resistance.

bioRxiv · Oct 1, 2021Microbiology

SDR enzymes oxidize specific lipidic alkynylcarbinols into cytotoxic protein-reactive species

P. Demange, E. Joly, J. Marcoux, P. R. A. Zanon, D. Listunov, P. Rulliere, C. Barthes, C. Noirot, J.-B. Izquierdo, K. Pradines, R. Hee, M. V. de Brito, M. Marcellin, R.-F. Serre, O. Bouchez, , S. Britton

The paper identifies SDR enzymes as bioactivators of lipidic alkynylcarbinols, converting them into cytotoxic electrophiles that modify proteins and induce cell death.

bioRxiv · Sep 15, 2021Biochemistry

Defining the function of OmpA in the Rcs stress response

J. Letoquart, K. Dekoninck, C. Laguri, P. Demange, R. Bevernaegie, J.-P. Simorre, O. Dehu, B. I. Iorga, B. Elias, S.-H. Cho, J.-F. Collet

This study investigates how OmpA interacts with RcsF in Escherichia coli, revealing that OmpA competes with IgaA for RcsF binding and regulates the Rcs stress response.

bioRxiv · Jul 15, 2020Microbiology

The effects of age at menarche and first sexual intercourse on reproductive and behavioural outcomes: a Mendelian randomization study

R. B. Lawn, H. M. Sallis, R. E. Wootton, A. E. Taylor, P. Demange, A. Fraser, I. S. Penton-Voak, M. R. Munafo

This study uses Mendelian randomization to examine if age at menarche and first sexual intercourse causally affect reproductive, educational, and behavioral outcomes in UK Biobank participants.

bioRxiv · Sep 20, 2018Evolutionary Biology