Author

P. R. Gafken

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

C. Lin· 2 shared A. Burian· 1 shared A. G. Paulovich· 1 shared A. L. Wilson· 1 shared C.-F. Tsai· 1 shared G. Longton· 1 shared J. A. Gustafson· 1 shared J. D. Lautz· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

C. Lin

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Author profile →

2 papers

Recent·Most cited

State-dependent protein-protein interactions mediating 4-1BB CAR Signaling

S. A. Ritmeester-Loy, J. D. Lautz, Y. Zhang-Wong, J. A. Gustafson, A. L. Wilson, C. Lin, P. R. Gafken, M. C. Jensen, R. Orentas, S. E. Smith

The paper identifies a network of protein interactions activated by 4-1BB CARs upon target engagement and shows that network activation magnitude correlates with IL-2 secretion.

bioRxiv · Jun 7, 2022 · PreprintImmunology

Multiplexed triage of candidate biomarkers in plasma using internal standard triggered-parallel reaction monitoring mass spectrometry

J. J. Kennedy, J. R. Whiteaker, R. G. Ivey, A. Burian, S. Chowdhury, C.-F. Tsai, T. Liu, C. Lin, O. Murillo, R. A. Lundeen, L. A. Jones, P. R. Gafken, G. Longton, K. D. Rodland, S. Skates, , A. G. Paulovich

This paper introduces an IS-PRM assay to prioritize plasma biomarkers for validation, showing improved sensitivity and precision over traditional methods.

bioRxiv · Sep 2, 2021 · PreprintCancer Biology