Author

P. R. Weigele

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Slyvka· 1 shared C. Alarcon· 1 shared C. Guan· 1 shared C. Venclovas· 1 shared D. Kazlauskas· 1 shared E. A. Raleigh· 1 shared E. Schildkraut· 1 shared G. B. Robb· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. Slyvka

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2 papers

Recent·Most cited

Modification of DNA by a viral enzyme and charged tRNA

R. M. B. Silva, A. Slyvka, Y.-J. Lee, C. Guan, S. R. Lund, E. A. Raleigh, K. Skowronek, M. Bochtler, P. R. Weigele

The paper demonstrates how the phage Mu enzyme Mom uses charged tRNA to hypermodify adenine in DNA and reports the first in vitro reconstitution of this process.

bioRxiv · Mar 24, 2023Biochemistry

Biochemically diverse CRISPR-Cas9 orthologs

G. Gasiunas, J. K. Young, T. Karvelis, D. Kazlauskas, T. Urbaitis, M. Jasnauskaite, M. Grusyte, S. Paulraj, P.-H. Wang, Z. Hou, S. K. Dooley, M. Cigan, C. Alarcon, N. D. Chilcoat, G. Bigelyte, , V. Siksnys

The paper characterizes the biochemical diversity of CRISPR-Cas9 orthologs, identifying varied PAM recognition and gRNA requirements across 79 Cas9 proteins.

bioRxiv · Apr 29, 2020 · PreprintBiochemistry