Author

P. Ramakrishnan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:host-pathogen & immune response· 2 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Brewer· 1 shared A. Weinberg· 1 shared J. Muller-Greven· 1 shared J. Penfield· 1 shared K. Zhang· 1 shared L. Zhang· 1 shared M. Buck· 1 shared R. Parameswaran· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Brewer

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

NF-kB c-Rel is dispensable for the development but is required for the cytotoxic function of NK cells

Y. Vicioso, K. Zhang, P. Ramakrishnan, R. Parameswaran

This study shows that c-Rel is essential for NK cell cytotoxic function but not for their development, as it regulates perforin and granzyme B expression.

bioRxiv · Jan 19, 2021Immunology

Molecular dynamics simulations and functional studies reveal that hBD-2 binds SARS-CoV-2 spike RBD and blocks viral entry into ACE2 expressing cells

L. Zhang, S. K. Ghosh, S. C. Basavarajappa, J. Muller-Greven, J. Penfield, A. Brewer, P. Ramakrishnan, M. Buck, A. Weinberg

The paper shows hBD-2 binds SARS-CoV-2 spike RBD and blocks viral entry into ACE2-expressing cells, with a KD of ~300 nM and IC50 of 2.4 μM.

bioRxiv · Jan 7, 2021 · PreprintBiochemistry