Cancer BiologybioRxiv
An immunogenic model of KRAS-mutant lung cancer for study of targeted therapy and immunotherapy combinations
J. Boumelha, S. de Carne Trecesson, E. Law…·J. Downward
This paper develops an immunogenic mouse model of KRAS-mutant lung cancer that responds to immunotherapy and reveals immune responses target endogenous retroviral antigens rather than neoantigens.
DOI 10.1158/0008-5472.can-22-0325