Author

P. Sant

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:clustering· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:scATAC-seq· 1 Assay:scRNA-seq· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

A. Ernst· 2 shared A. Li· 2 shared O. Stegle· 2 shared A. Abdollahi· 1 shared A. Korshunov· 1 shared F. Devens· 1 shared F. Winkler· 1 shared G. Philippos· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

A. Ernst

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2 papers

Recent·Most cited

HIPSD&R-seq enables scalable genomic copy number and transcriptome profiling

O. Lazareva, J. P. Malm, M. Simovic-Lorenz, G. Philippos, P. Sant, U. Parekh, L. Hammann, A. Li, U. Yildiz, M. Marttinen, J. B. Zaugg, K. M. Noh, O. Stegle, A. Ernst

HIPSD&R-seq profiles genomic copy number and transcriptomes in thousands of cells, enabling rare clone detection in human cell models and primary tissue.

bioRxiv · Oct 9, 2023 · PreprintCancer Biology

Spatial and temporal transcriptomics of SHH-medulloblastoma with chromothripsis identifies multiple genetic clones that resist to treatment and lead to relapse

I. Kats, H. S. Schreiber, M. Simovic, P. Sant, J.-P. Mallm, A. Li, P. Velmurugan, S. Weil, F. Devens, M. Sill, M. Jugold, M. Moustafa, A. Abdollahi, F. Winkler, A. Korshunov, , A. Ernst

This study uses spatial transcriptomics to analyze chromothriptic medulloblastomas, revealing higher intra-tumour heterogeneity, treatment resistance, and relapse mechanisms through clone-specific features.

bioRxiv · Mar 3, 2023 · PreprintCancer Biology