Author

J. B. Zaugg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:scRNA-seq· 3 Assay:bulk RNA-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:clustering· 2 Approach:deep learning· 2

Frequent Co-Authors

A. Mathioudaki· 2 shared I. Berest· 2 shared S. Dietrich· 2 shared T. Roider· 2 shared W. Huber· 2 shared A. Cvejic· 1 shared A. Ernst· 1 shared A. Horlova· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

A. Mathioudaki

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Author profile →

5 papers

Recent·Most cited

A single-cell multi-omic and spatial atlas of B cell lymphomas reveals differentiation drives intratumor heterogeneity

D. Fitzgerald, T. Roider, M. A. Baertsch, A. Kibler, A. Horlova, E. K. Chung, H. Voehringer, A. Mathioudaki, B. Budeus, V. Passerini, M. Knoll, J. Mammen, L. Li, L. Caille, F. Czernilofsky, , W. Huber

This study reveals that cellular differentiation drives intratumor heterogeneity in B-cell lymphomas, with distinct maturation states associated with different survival outcomes.

bioRxiv · Nov 6, 2023 · PreprintCancer Biology

HIPSD&R-seq enables scalable genomic copy number and transcriptome profiling

O. Lazareva, J. P. Malm, M. Simovic-Lorenz, G. Philippos, P. Sant, U. Parekh, L. Hammann, A. Li, U. Yildiz, M. Marttinen, J. B. Zaugg, K. M. Noh, O. Stegle, A. Ernst

HIPSD&R-seq profiles genomic copy number and transcriptomes in thousands of cells, enabling rare clone detection in human cell models and primary tissue.

bioRxiv · Oct 9, 2023 · PreprintCancer Biology

Combinatorial drug-microenvironment interaction mapping reveals cell-extrinsic drug resistance mechanisms and clinically relevant patient subgroups in CLL

P.-M. Bruch, H. A. R. Giles, C. Kolb, S. A. Herbst, T. Becirovic, T. Roider, J. Lu, S. Scheinost, L. Wagner, J. Huellein, I. Berest, M. Kriegsmann, K. Kriegsmann, C. Zgorzelski, P. Dreger, , S. Dietrich

This paper maps drug-microenvironment interactions in CLL to identify resistance mechanisms and patient subgroups, revealing how microenvironmental stimuli and genetic alterations influence drug response.

bioRxiv · Jul 23, 2021 · PreprintCancer Biology

Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype

R. Guha, A. Mathioudaki, S. Doumbo, D. Doumtabe, J. Skinner, G. Arora, S. Siddiqui, S. Li, K. Kayentao, A. Ongoiba, J. B. Zaugg, B. Traore, P. D. Crompton

This paper shows that repeated Plasmodium falciparum infections reprogram human monocytes to a regulatory phenotype, reducing inflammatory responses during subsequent infections.

bioRxiv · Oct 21, 2020Immunology

Integrative Single-cell RNA-Seq and ATAC-Seq Analysis of Human Developmental Haematopoiesis

A. M. Ranzoni, A. Tangherloni, I. Berest, S. G. Riva, B. Myers, P. M. Strzelecka, J. Xu, E. Panada, I. Mohorianu, J. B. Zaugg, A. Cvejic

The paper uses scRNA-Seq and scATAC-Seq to analyze human blood cells, identifying proliferative progenitors and epigenetic priming in haematopoiesis.

bioRxiv · May 6, 2020 · PreprintCell Biology