Polarly localized EccE1is required for ESX-1 function and stabilization of ESX-1 membrane proteins in Mycobacterium tuberculosis
P. Soler-Arnedo, C. Sala, M. Zhang, S. T. Cole, J. Piton
This study identifies EccE1 as a critical membrane protein required for ESX-1 function and stabilization of ESX-1 membrane proteins in Mycobacterium tuberculosis, with deletion of eccE1 reducing levels of other ESX-1 components and attenuating bacterial virulence.
bioRxiv · Oct 30, 2019Microbiology