Author

P. Stavropoulos

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Immunology· 1

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Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

F. N. Papavasiliou· 1 shared N. G. Economos· 1 shared R. K. Delker· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperImmunology

F. N. Papavasiliou

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1 paper

Recent·Most cited

Genetic loss of the ubiquitin ligase RNF126, an AID interacting partner and modifier, affects strand targeting during somatic hypermutation of antibody genes

N. G. Economos, R. K. Delker, P. Stavropoulos, F. N. Papavasiliou

This study shows that RNF126 ubiquitination of AID is necessary for proper strand targeting during SHM, leading to G>C mutation bias and reduced indels in the variable region.

bioRxiv · Nov 14, 2018 · PreprintImmunology