Signature activities of 20S proteasome include degradation of the ubiquitin-tag with the protein under hypoxia
I. Sahu, S. M. Mali, P. Sulkshane, A. Rozenberg, C. Xu, R. Morag, M. P. Sahoo, S. K. Singh, Z. Ding, Y. Wang, S. Day, Y. Cong, O. Kleifeld, A. Brik, M. H. Glickman
The paper identifies the 20S proteasome's ability to degrade ubiquitin-tagged proteins under hypoxia and shows its role in improving cell survival.
bioRxiv · Dec 20, 2019 · PreprintBiochemistry