A fully defined pluripotent stem cell derived multi-liver-cell model for steatohepatitis and fibrosis
M. K. Gautam, B. Toprakhisar, M. Van Haele, A. Antoranz, R. Boon, F. Chesnais, J. De Smedt, T. I. Idoype, M. Canella, P. Tilliole, J. De Boeck, T. Tricot, M. Bajaj, A. Ranga, F. M. Bosisio, , C. M. Verfaillie
The paper develops a co-culture system of pluripotent stem cell-derived liver cells to model NASH-induced steatosis, inflammation, and fibrosis.
bioRxiv · Sep 3, 2020Bioengineering