Modular, ultra-stable, and highly parallel protein force spectroscopy in magnetic tweezers using peptide linkers
A. Löf, P. U. Walker, S. M. Sedlak, T. Obser, M. A. Brehm, M. Benoit, J. Lipfert
This paper introduces a modular magnetic tweezers approach using peptide linkers to enable ultra-stable, parallel protein force spectroscopy in the low force regime, revealing new insights into protein unfolding and activation mechanisms.
bioRxiv · Dec 10, 2018Biophysics