Author

Pablo Mantilla

Cold Spring Harbor Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genomics· 1

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Approach:diffusion model· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:sequence-to-function modeling· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Alejandra DurániD· 1 shared Anirban SarkariD· 1 shared Da-Wei LiniD· 1 shared Jessica ZhouiD· 1 shared Kaarina Hanington· 1 shared Kenneth ChangiD· 1 shared Masayuki Nagai· 1 shared Nirali Somia· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Alejandra DuránORCID

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1 paper

Recent·Most cited

Designing DNA With Tunable Regulatory Activity Using Discrete Diffusion

Anirban Sarkar, Alejandra Durán, Yiyang Yu, Da-Wei Lin, Yijie Kang, Nirali Somia, Pablo Mantilla, Jessica Zhou, Masayuki Nagai, Ziqi Tang, Kaarina Hanington, Kenneth Chang, Peter K. Koo

This paper introduces D3, a generative model for designing regulatory DNA with tunable activity, showing improved performance over baselines in sequence generation and activity prediction.

bioRxiv · May 23, 2024 · PreprintGenomics