Author

Alejandra Durán

Cold Spring Harbor LaboratoryORCID 0000-0001-8691-5612Unclaimed ORCID profile · follow to get notified of new preprints

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Alejandra Durán1 paper

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Approach:diffusion model· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:sequence-to-function modeling· 1 Research Focus:software / tool· 1

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Anirban SarkariD· 1 shared Da-Wei LiniD· 1 shared Jessica ZhouiD· 1 shared Kaarina Hanington· 1 shared Kenneth ChangiD· 1 shared Masayuki Nagai· 1 shared Nirali Somia· 1 shared Pablo Mantilla· 1 shared

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Anirban SarkarORCID

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Recent·Most cited

GenomicsbioRxivPreprintMay 23, 2024

Designing DNA With Tunable Regulatory Activity Using Discrete Diffusion

Anirban Sarkar, Alejandra Durán, Yiyang Yu…·Peter K. Koo

This paper introduces D3, a generative model for designing regulatory DNA with tunable activity, showing improved performance over baselines in sequence generation and activity prediction.

28 citations

humanDNA methylation

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