Single-cell transcriptional dynamics in a living vertebrate
Elizabeth Eck, Bruno Moretti, Brandon H. Schlomann, Jordão Bragantini, Merlin Lange, Xiang Zhao, Shruthi VijayKumar, Guillaume Valentin, Cristina Loureiro, Pablo Perez Franco, Chloé Jollivet, Virginie Braman, Baldemar Motomochi, Löıc A. Royer, Andrew C. Oates, Hernán G. García
This study measures single-cell transcriptional dynamics in zebrafish embryos using MS2-MCP labeling and light sheet microscopy, revealing discrete transcriptional bursts in the segmentation clock.
Cell Systems · Aug 19, 2026Peer-reviewedDevelopmental Biology