miR-146a-3p packaged in small extracellular vesicles triggers fetal membrane inflammation in response to viral dsRNA through activation of Toll-like Receptor 7 and 8
Hanah M. Georges, Abigail C. Fischer, Paloma Casanova, Vikki M. Abrahams
The paper shows that miR-146a-3p in small extracellular vesicles from viral-stimulated fetal membranes activates TLR7/8 to drive inflammation.
bioRxiv · Jul 29, 2025 · PreprintImmunology