Author

Hanah M. Georges

Yale UniversityORCID 0000-0001-9065-9885Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:differential expression· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Vikki M. AbrahamsiD· 3 shared Kimberly Ann YonkersiD· 2 shared Megan E Kelleher· 2 shared Ryan Wellington LoganiD· 2 shared Abigail C. FischeriD· 1 shared Elle M. McCauley· 1 shared Lisa V Salmeron· 1 shared Paloma Casanova· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 22 mutual co-author links

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3 shared papersImmunology

Vikki M. AbrahamsORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 1, 2026

Methadone Triggers Fetal Membrane Sterile Inflammation Through Innate Immune and Opioid Receptor Signaling

Megan E Kelleher, Hanah M. Georges, Lisa V Salmeron…·Vikki M. Abrahams

This study shows methadone induces sterile inflammation in fetal membranes via TLR7, TLR8, NLRP3, opioid receptors, and NFκB/MAPK signaling in both human and mouse models.

DOI 10.64898/2026.09.25.754438

humanmouse

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ImmunologybioRxivPreprintJul 29, 2025

miR-146a-3p packaged in small extracellular vesicles triggers fetal membrane inflammation in response to viral dsRNA through activation of Toll-like Receptor 7 and 8

Hanah M. Georges, Abigail C. Fischer, Paloma Casanova, Vikki M. Abrahams

The paper shows that miR-146a-3p in small extracellular vesicles from viral-stimulated fetal membranes activates TLR7/8 to drive inflammation.

2 citations

humanexperimental assay

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ImmunologyJournal of Reproductive ImmunologyPeer-reviewedNov 22, 2024

Buprenorphine Induces Human Fetal Membrane Sterile Inflammation

Tatyana Lynn, Megan E Kelleher, Hanah M. Georges…·Vikki M. Abrahams

This study shows buprenorphine induces sterile inflammation in human fetal membranes, increasing preterm birth risk via TLR4, NLRP3, and MAPK pathways.

3 citations

humanbulk RNA-seq

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