Author

Pamela Lecras

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Gaëtan RiouiD· 3 shared Pauline NeveuiD· 3 shared Alizée Hugede· 2 shared Amandine Robac· 2 shared Axelle Blondin· 2 shared Clémence Raimond· 2 shared Laurine Moncomble· 2 shared Matthis Brodier· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Gaëtan RiouORCID

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3 papers

Recent·Most cited

Altered therapeutic capacities of olfactory ensheathing cells caused by a lesion in an autologous transplantation model for the treatment of spinal cord injury.

Quentin Delarue, Matthis Brodier, Pauline Neveu, Laurine Moncomble, Clémence Raimond, Amandine Robac, Alizée Hugede, Axelle Blondin, Fannie Semprez, Pamela Lecras, Gaëtan Riou, Nicolas Guérout

This study shows that olfactory ensheathing cells from previously injured animals have reduced therapeutic potential in spinal cord injury treatment compared to healthy donor cells.

Stem Cell Research & Therapy · Nov 21, 2025Peer-reviewedNeuroscience

Anti-PD-1/PD-L1 Therapy Triggers Cognitive Deficits and Anxiety-Like Behaviors Through Tumor-Initiated Neuroinflammatory Niches in Male Mice

C. Nicola, Martin Pédard, Martine Dubois, Laurence Desrues, Pauline Neveu, Gaëtan Riou, Ian Johnston, Paul Dembele Kleouforo, Pamela Lecras, David Vaudry, Sahil Adriouch, Florence Joly, Pascal Hilber, Olivier Wurtz, Hélène Castel

This study shows that anti-PD-1/PD-L1 therapy in mice with cancer causes cognitive deficits and anxiety through neuroinflammatory processes triggered by tumor-associated immune changes.

bioRxiv · Sep 3, 2025 · PreprintCancer Biology

Lesion-induced impairment of therapeutic capacities of olfactory ensheathing cells in an autologous transplantation model for treatment of spinal cord injury

Quentin Delarue, Matthis Brodier, Pauline Neveu, Laurine Moncomble, Alizée Hugede, Axelle Blondin, Amandine Robac, Clémence Raimond, Pamela Lecras, Gaëtan Riou, Nicolas Guérout

The paper shows that spinal cord injury impairs the therapeutic potential of olfactory ensheathing cells used in autologous transplantation.

bioRxiv · Apr 19, 2024 · PreprintNeuroscience