Cancer BiologybioRxivPreprint
Anti-PD-1/PD-L1 Therapy Triggers Cognitive Deficits and Anxiety-Like Behaviors Through Tumor-Initiated Neuroinflammatory Niches in Male Mice
C. Nicola, Martin Pédard, Martine Dubois…·Hélène Castel
This study shows that anti-PD-1/PD-L1 therapy in mice with cancer causes cognitive deficits and anxiety through neuroinflammatory processes triggered by tumor-associated immune changes.
DOI 10.1101/2025.09.03.673981