The CHCHD2-CHCHD10 protein complex is modulated by mitochondrial dysfunction and alters lipid homeostasis in the mouse brain.
Jule Gerlach, Paola Pireddu, Xiaoqun Zhang, Simon Wetzel, Mara Mennuni, Dusanka Milenkovic, Hendrik Nolte, Fernanda da Silva Rodrigues, Niclas Branzell, Ibrahim Kaya, Rodolfo García-Villegas, Diana Rubalcava-Gracia, David Alsina, Regina Feederle, Per E. Andrén, , Roberta Filograna
This study investigates the role of the CHCHD2-CHCHD10 protein complex in mitochondrial dysfunction and lipid homeostasis in mice, showing its importance in motor function and disease resistance.
Cell Death and Disease · Oct 6, 2025Peer-reviewedNeuroscience