Normalization of Prefrontal Network Dynamics Prevents Cognitive Impairments After Developmental Insult
Mohamed R. Khalife, Patrick E. Jasinski, Khalil Abed Rabbo, Mohamed Ouardouz, J. Matthew Mahoney, Rod C. Scott, Amanda E. Hernan
This study shows that developmental insults impair mPFC network dynamics, and ACTH treatment prevents these impairments, preserving cognitive function through restored network organization.
bioRxiv · May 30, 2025 · PreprintNeuroscience