Author

Patrick O’Day

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Amy H. ZhaoiD· 1 shared Anthony G. K. GarciaiD· 1 shared Douglas F. CoveyiD· 1 shared Mingxing QianiD· 1 shared Prasanthi P. KogantiiD· 1 shared Richard Joseph AuchusiD· 1 shared Vimal SelvarajiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

Amy H. ZhaoORCID

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1 paper

Recent·Most cited

Target validation uncouples TSPO from 19-Atriol-mediated inhibition of steroidogenesis and reveals true enzymatic targets

Amy H. Zhao, Prasanthi P. Koganti, Mingxing Qian, Anthony G. K. Garcia, Patrick O’Day, Richard Joseph Auchus, Douglas F. Covey, Vimal Selvaraj

This study shows 19-Atriol inhibits steroidogenesis by directly targeting 3β-HSD and other enzymes, not via TSPO, resolving a long-standing mechanistic confusion.

bioRxiv · Sep 25, 2025 · PreprintPharmacology & Toxicology