A complex osteoporotic milieu is associated with arterial stiffening and PDGF-BB-mediated calcification of human smooth muscle cells
Wera Pustlauk, Toralf Roch, Ioanna Maria Dimitriou, Arturo Blázquez Navarro, Ulrik Stervbo, Moritz Anft, Julian Braun, Rainer Wirth, Maryam Pourhassan, Bjoern Buehring, Doruk Akgün, Patrizia Wehler, Sarah Skrzypczyk, Gerald Grütz, Sven Rahmann, , Sven Geißler
This study identifies a complex osteoporotic systemic milieu linked to arterial stiffening and PDGF-BB-mediated vascular calcification in human smooth muscle cells.
bioRxiv · Oct 25, 2025 · PreprintCell Biology