Identification of the negamycin split biosynthetic gene cluster in Kitasatospora purpeofusca ATCC21470
Alena Strüder, Saad Touzi, Mayarasmi Long, Erik Mingyar, Carolin Schwitalla, Anne Berscheid, Sophie Bourcier, Heike Brötz‐Oesterhelt, Emmanuelle Darbon, Paul Frankenreiter, Mirita Franz‐Wachtel, Christian Geibel, Theresa Anisja Harbig, Chambers C. Hughes, Boris Maček, , Evi Stegmann
This study identifies and characterizes the negamycin biosynthetic gene cluster in Kitasatospora purpeofusca, enabling scalable production through heterologous expression.
bioRxiv · Jul 31, 2025 · PreprintMicrobiology