Author

Paul Girardeau

Université de Bordeaux

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:rat· 3 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Audrey Durand· 4 shared Serge H. AhmediD· 2 shared Boris Gutkin· 1 shared Caroline Vouillac-Mendoza· 1 shared Caroline Vouillac‐MendozaiD· 1 shared Karine GuillemiD· 1 shared Luana FreeseiD· 1 shared Ludivine CanchyiD· 1 shared

Activity by Year

2015-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersNeuroscience

Audrey Durand

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Loss of resistance to punishment of cocaine use after prior experience

Audrey Durand, Paul Girardeau, Luana Freese, Serge H. Ahmed

The paper shows that resistance to punishment in cocaine use is not stable, as rats become less resistant after retesting and suppress intake with lower punishment intensity.

Neuropsychopharmacology · Aug 24, 2021Peer-reviewedNeuroscience

Pharmacokinetics trumps pharmacodynamics during cocaine choice: a reconciliation with the dopamine hypothesis of addiction

Ludivine Canchy, Paul Girardeau, Audrey Durand, Caroline Vouillac‐Mendoza, Serge H. Ahmed

This study reconciles the dopamine hypothesis of addiction with cocaine choice behavior by showing pharmacokinetics, not pharmacodynamics, determines reward preference in rats.

HAL · Jan 1, 2021Peer-reviewedNeuroscience

Persistent vulnerability to relapse despite complete extinction of cocaine craving

Paul Girardeau, Sylvia Navailles, Audrey Durand, Caroline Vouillac-Mendoza, Karine Guillem, Serge H Ahmed

This study shows that complete extinction of cocaine priming in rats does not prevent relapse, suggesting the presence of extinction-resistant behavior that contributes to relapse vulnerability.

bioRxiv · Apr 26, 2016Animal Behavior & Cognition

An integrated homeostatic reinforcement learning theory of motivation explains the transition to cocaine addiction

Mehdi Keramati, Audrey Durand, Paul Girardeau, Boris Gutkin, Serge Ahmed

This paper develops a computational theory integrating homeostatic regulation and reinforcement learning to explain cocaine addiction, showing how chronic use leads to increased drug-seeking behavior and relapse.

bioRxiv · Oct 15, 2015Neuroscience