NeuroscienceHALPeer-reviewed
Pharmacokinetics trumps pharmacodynamics during cocaine choice: a reconciliation with the dopamine hypothesis of addiction
Ludivine Canchy, Paul Girardeau, Audrey Durand…·Serge H. Ahmed
This study reconciles the dopamine hypothesis of addiction with cocaine choice behavior by showing pharmacokinetics, not pharmacodynamics, determines reward preference in rats.
30 citations