Author

Paul Hubinger

Medical University of Vienna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Florian KellneriD· 1 shared Gerhard J. SchütziD· 1 shared Janett GöhringiD· 1 shared Johannes B. HuppaiD· 1 shared José Luis Toca-HerreraiD· 1 shared Josephine Wieland· 1 shared Lukas SchrangliD· 1 shared Reinhard ObstiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Florian KellnerORCID

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1 paper

Recent·Most cited

CD4+ T-cells create a stable mechanical environment for force-sensitive TCR:pMHC interactions

Lukas Schrangl, Florian Kellner, René Platzer, Vanessa Mühlgrabner, Paul Hubinger, Josephine Wieland, Reinhard Obst, José Luis Toca-Herrera, Johannes B. Huppa, Gerhard J. Schütz, Janett Göhring

The paper quantifies mechanical forces on TCR:pMHC interactions in CD4+ T-cells, finding low forces that do not affect bond lifetimes, suggesting the immunological synapse stabilizes antigen recognition.

Nature Communications · Aug 14, 2025Peer-reviewedImmunology