Author

Paul J. Lombroso

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Jian Xu· 2 shared Manavi ChatterjeeiD· 2 shared Pradeep K. Kurup· 2 shared Annemarie DedekiD· 1 shared Antoine G. GodiniD· 1 shared Chaya M Kandegedara· 1 shared Eve Chung TsaiiD· 1 shared Geneviève Glavina· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersNeuroscience

Jian Xu

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3 papers

Recent·Most cited

Sexual dimorphism in a neuronal mechanism of spinal hyperexcitability across rodent and human models of pathological pain

Annemarie Dedek, Jian Xu, Louis-Étienne Lorenzo, Antoine G. Godin, Chaya M Kandegedara, Geneviève Glavina, Jeffrey Landrigan, Paul J. Lombroso, Yves De Koninck, Eve Chung Tsai, Michael E. Hildebrand

The paper identifies a sex-specific neuronal mechanism of spinal hyperexcitability in pain models, showing differences in BDNF signaling between male and female rodents and humans.

Brain · Oct 26, 2021Peer-reviewedNeuroscience

STEP inhibition prevents Aβ mediated damage in dendritic complexity and spine density in Alzheimer's disease.

Manavi Chatterjee, Jeemin Kwon, Jessie Benedict, Marija Kamceva, Pradeep K. Kurup, Paul J. Lombroso

This study shows that STEP inhibition improves cognitive function and synaptic connectivity in Alzheimer's disease models.

Experimental Brain Research · Jan 9, 2021Peer-reviewedNeuroscience

Inhibition of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) Activity Reverses Behavioral Deficits in a Rodent Model of Autism.

Manavi Chatterjee, Priya Singh, Jian Xu, Paul J. Lombroso, Pradeep K. Kurup

This study investigates the role of STEP in a VPA-induced ASD mouse model and finds that STEP inhibition reverses behavioral deficits.

Behavioural Brain Research · May 24, 2020Peer-reviewedNeuroscience