The structure and composition of native human nucleosomes
Xavier J. Reid, Meghna Sobti, Yi C. Zeng, Yichen Zhong, Chandrika N. Deshpande, Paul Young, Simon H. J. Brown, Jason K. K. Low, Alastair G. Stewart, Joel P. Mackay
This study reports the high-resolution cryo-EM structure of native human nucleosomes from HEK293 cells and provides mass spectrometry analysis of histone modifications.
bioRxiv · Oct 10, 2025 · PreprintBiochemistry