Identification of the main barriers to Ku accumulation in chromatin
Madeleine Bossaert, Andrew Moreno, António Peixoto, Marie‐Jeanne Pillaire, Pauline Chanut, Philippe Frit, Patrick Calsou, Joseph J. Loparo, Sébastien Britton
The paper identifies mechanisms that limit Ku protein accumulation in chromatin, showing DNA-PKcs blocks Ku entry, and two additional mechanisms restrict Ku levels in the absence of DNA-PKcs.
Cell Reports · Jul 26, 2024Peer-reviewedMolecular Biology