NeuroscienceJournal of NeurosciencePeer-reviewed
Somatostatin-positive Interneurons Contribute to Seizures in SCN8A Epileptic Encephalopathy
Eric R. Wengert, Raquel M. Miralles, Kyle C. A. Wedgwood…·Manoj K. Patel
This study shows that somatostatin-positive interneurons with SCN8A mutations contribute to seizures by causing hyperexcitability and depolarization block.
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