Kyle C. A. Wedgwood

This paper introduces a plasmonic imaging technique to track bioelectrical interactions in live pancreatic beta-cell networks and demonstrates its application in studying electrical communication relevant to diabetes.

This paper introduces DeepHM, a method combining deep learning and biophysical modeling to infer ion channel conductance changes in Alzheimer's mouse models.

The paper identifies a NO-mediated retrograde signaling pathway in ciliary photoreceptor cells that gates a UV avoidance circuit in Platynereis dumerilii larvae.

This study shows that somatostatin-positive interneurons with SCN8A mutations contribute to seizures by causing hyperexcitability and depolarization block.

This study shows that Vangl2 regulates cytoneme dynamics, affecting Wnt/{beta}-catenin signaling and tissue patterning in vertebrates.

This study develops a mathematical model to explore how cortisol rhythms affect glucose utilization and disease states like type 2 diabetes.

The paper models cardiopulmonary responses to maximal aerobic exercise in CF patients to predict anaerobic threshold and improve personalized exercise programs.