Author

Penelope Pennoyer

Goethe University Frankfurt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Andreas Michael ZeiheriD· 2 shared David JohniD· 2 shared Evelyn UllrichiD· 2 shared Franziska Ganß· 2 shared Simone-Franziska GlaseriD· 2 shared Stefanie DimmeleriD· 2 shared Wesley Tyler AbplanalpiD· 2 shared Alisa Debes· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCell Biology

Andreas Michael ZeiherORCID

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2 papers

Recent·Most cited

Haematopoietic loss of KDM6A impairs cardiac recovery in heartfailure via epigenetic reprogramming of myeloid cells

Emmanouil G Solomonidis, Dennis Hecker, Mariana Shumliakivska, Julian Leberzammer, Ariane Fischer, Minh-Thuy Katschke, Melanie Bendel, Lara Korth, Bianca Schuhmacher, Laura Rumpf, Simone-Franziska Glaser, Katja Schmitz, Guillermo Luxán, Silke Frenz, Penelope Pennoyer, , Sebastian Cremer

This study shows that loss of KDM6A in hematopoietic cells impairs cardiac recovery after heart failure by causing epigenetic changes in myeloid cells that increase inflammation and worsen cardiac outcomes.

bioRxiv · Dec 2, 2025 · PreprintCell Biology

Deciphering human heart failure with preserved ejection fraction (HFpEF) at single cell resolution

Lukas Zanders, Simone-Franziska Glaser, Mariano Ruz Jurado, Moritz Brandt, David John, Luka Nicin, David Rodríguez Morales, Wesley Tyler Abplanalp, Tara Procida‐Kowalski, Franziska Ganß, Evelyn Ullrich, Alisa Debes, Penelope Pennoyer, Marek Bartkuhn, Reinhard B Dettmeyer, , Stefanie Dimmeler

This paper uses single-nucleus RNA sequencing to analyze HFpEF myocardium, identifying transcriptional changes in cardiomyocytes, endothelial cells, fibroblasts, and macrophages that suggest metabolic, inflammatory, and fibrotic mechanisms.

European Heart Journal · Nov 1, 2025Peer-reviewedCell Biology