Rescue of a developmental arrest caused by a C. elegans heat-shock transcription-factor mutation by loss of ribosomal S6-kinase activity
Peter J. Chisnell, T Richard Parenteau, Elizabeth M.H. Tank, Kaveh Ashrafi, Cynthia J. Kenyon
This study identifies that loss of rsks-1/S6-Kinase rescues developmental arrest in C. elegans hsf-1 mutants, revealing an unexplained regulatory link between heat-shock transcription factors and the TOR pathway during development.
bioRxiv · Apr 28, 2018 · PreprintGenetics