Functional Profiling of Thousands of Sequence-Diverse Protease Homologs with GROQ-seq
James R. McLellan, Svetlana P. Ikonomova, Shwetha Sreenivasan, Alan N. Amin, Catherine Baranowski, Amanda Reider Apel, Peter Kelly, D. L. Ross, Aviv Spinner
The paper uses GROQ-seq to profile function across a diverse protease library, showing robust activity across sequence divergence.
bioRxiv · May 5, 2026 · PreprintSynthetic Biology