Locomotor deficits in ALS mice are paralleled by loss of V1-interneuron-connections onto fast motor neurons
Ilary Allodi, Roser Montañana-Rosell, Raghavendra Selvan, Peter Löw, Ole Kiehn
The paper shows that loss of inhibitory synapses from V1 interneurons onto fast motor neurons precedes ALS progression and contributes to locomotor deficits.
Nature Communications · May 31, 2021Peer-reviewedNeuroscience