Author
University of Eastern Finland
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Mari Takalo, Heli Jeskanen, Taisia Rõlova…·Mikko Hiltunen
This study shows that the PLCgamma2-P522R variant reduces beta-amyloid pathology and enhances microglial function in AD models, suggesting an anti-ageing mechanism.
Hannah Rostalski, Tomi Hietanen, Dorit B. Hoffmann…·Annakaisa Haapasalo
This study shows that C9orf72 repeat expansion in iPSC-derived microglia from FTD patients leads to increased phagocytic activity and reduced autophagosomal-lysosomal vesicles.
Teemu Natunen, Henna Martiskainen, Mikael Marttinen…·Mikko Hiltunen
This study shows that a diabetic phenotype in mice and humans reduces microglial response to β-amyloid plaques, linking T2D and AD pathologies.
Mari Takalo, Rebekka Wittrahm, Benedikt Wefers…·Christian Haass
This study identifies a protective Plcγ2-P522R variant in Alzheimer's disease by showing it enhances microglial functions like phagocytosis and survival.
Maxime Sartori, Tiago Mendes, Shruti Desai…·Jean‐Charles Lambert
This study shows BIN1 overexpression rescues long-term memory deficits in Tau-overexpressing mice and identifies Thr348 phosphorylation as a key regulator of BIN1-Tau interaction.