Author
University of Eastern FinlandORCID 0000-0001-9269-5492Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Nadine Huber, Tomi Hietanen, Sami Heikkinen…·Annakaisa Haapasalo
This study shows that iPSC-derived neurons from FTD patients exhibit synaptic dysfunction, DNA damage, and C9-HRE-related pathologies, supporting synaptic dysfunction as a key factor in FTD.
Heli Jeskanen, Sami Heikkinen, Inka Kervinen…·Mikko O. Hiltunen
The paper examines how protective PLCG2 variants delay Alzheimer's onset in APOE ε4 carriers and identifies associated plasma biomarkers.
Hannah Rostalski, Tomi Hietanen, Dorit B. Hoffmann…·Annakaisa Haapasalo
This study shows that C9orf72 repeat expansion in iPSC-derived microglia from FTD patients leads to increased phagocytic activity and reduced autophagosomal-lysosomal vesicles.
Dorit B. Hoffmann, Ville E. Korhonen, Hannah Rostalski…·Annakaisa Haapasalo