Author

Philip Ginsbach

German Cancer Research Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:variant calling· 3 Assay:whole-genome sequencing· 3 Approach:benchmark study· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Barbara HutteriD· 3 shared Benedikt BrorsiD· 3 shared Ivo BuchhalteriD· 2 shared Karsten RippeiD· 2 shared Lars FeuerbachiD· 2 shared Lina SieverlingiD· 2 shared Roland EilsiD· 2 shared Adam A. AbeshouseiD· 1 shared

Activity by Year

2015-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersGenomics

Barbara HutterORCID

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3 papers

Recent·Most cited

Genomic footprints of activated telomere maintenance mechanisms in cancer

Lina Sieverling, Chen Hong, Sandra D. Koser, Philip Ginsbach, Kortine Kleinheinz, Barbara Hutter, Delia M. Braun, Isidro Cortés‐Ciriano, Ruibin Xi, Rolf Kabbe, Peter J. Park, Roland Eils, Matthias Schlesner, PCAWG-Structural Variation Working Group, Kadir C. Akdemir, , Rehan Akbani

The paper analyzes whole-genome sequencing data from cancer samples to identify genomic footprints of telomere maintenance mechanisms, finding specific telomere variant repeat patterns associated with ATRX/DAXX mutations.

Nature Communications · Feb 5, 2020Peer-reviewedGenomics

TelomereHunter: telomere content estimation and characterization from whole genome sequencing data

Lars Feuerbach, Lina Sieverling, Katharina Deeg, Philip Ginsbach, Barbara Hutter, Ivo Buchhalter, Paul A Northcott, Peter Lichter, Stefan M Pfister, David TW Jones, Karsten Rippe, Benedikt Brors

TelomereHunter estimates and characterizes telomere content from whole genome sequencing data in cancer studies.

bioRxiv · Jul 23, 2016Bioinformatics

A Comprehensive Assessment of Somatic Mutation Calling in Cancer Genomes

Tyler S Alioto, Sophia Derdak, Timothy A Beck, Paul C Boutros, Lawrence Bower, Ivo Buchhalter, Matthew D Eldridge, Nicholas J Harding, Lawrence Edward Heisler, Eivind Hovig, David T W Jones, Andrew G Lynch, Sigve Nakken, Paolo Ribeca, Anne-Sophie Sertier, , Rolf Kab

This study benchmarks somatic mutation calling in cancer genomes, identifying inconsistencies and proposing solutions to improve accuracy.

Nature Communications · Dec 9, 2015Peer-reviewedGenomics