Author

Sophia Derdak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1

Frequent Co-Authors

Akihiro FujimotoiD· 2 shared Anne-Sophie Sertier· 2 shared Barbara HutteriD· 2 shared Benedikt BrorsiD· 2 shared Ivo BuchhalteriD· 2 shared Laurie Tonon· 2 shared Natalie JägeriD· 2 shared Paolo RibecaiD· 2 shared

Activity by Year

2015-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Akihiro FujimotoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Effects of pharmacological calcimimetics on colorectal cancer cells over-expressing the human calcium-sensing receptor

Luca Iamartino, Taha Elajnaf, Katharina Gall, Jacquelina David, Teresa Manhardt, Petra Heffeter, Michael Grusch, Sophia Derdak, Sabina Baumgartner-Parzer, Martin Schepelmann, Enikö Kallay

This study examines the effects of calcimimetics on CaSR-overexpressing colorectal cancer cells, finding increased inflammation markers in vitro but no tumor suppression in vivo.

bioRxiv · Jul 9, 2020Cancer Biology

A Comprehensive Assessment of Somatic Mutation Calling in Cancer Genomes

Tyler S Alioto, Sophia Derdak, Timothy A Beck, Paul C Boutros, Lawrence Bower, Ivo Buchhalter, Matthew D Eldridge, Nicholas J Harding, Lawrence Edward Heisler, Eivind Hovig, David T W Jones, Andrew G Lynch, Sigve Nakken, Paolo Ribeca, Anne-Sophie Sertier, , Rolf Kab

This study benchmarks somatic mutation calling in cancer genomes, identifying inconsistencies and proposing solutions to improve accuracy.

Nature Communications · Dec 9, 2015Peer-reviewedGenomics

A comprehensive multicenter comparison of whole genome sequencing pipelines using a uniform tumor-normal sample pair

Ivo Buchhalter, Barbara Hutter, Tyler S. Alioto, Timothy A. Beck, Paul C. Boutros, Benedikt Brors, Adam P. Butler, Sasithorn Chotewutmontri, Robert E. Denroche, Sophia Derdak, Nicolle Diessl, Lars Feuerbach, Akihiro Fujimoto, Susanne Gröbner, Marta Gut, , on behalf of the ICGC Verification and Validation Working Group

This study compares whole genome sequencing pipelines across five centers using a uniform tumor-normal sample pair, identifying factors affecting output consistency.

bioRxiv · Jun 12, 2015 · PreprintGenomics