Author

Philipp Lewe

University Medical Center Hamburg-Eppendorf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Aigars JirgensonsiD· 1 shared Ben F. LuisiiD· 1 shared Björn WindshügeliD· 1 shared Cristina D. CruziD· 1 shared Emmanouela Petsolari· 1 shared Fatima-Zahra Rachad· 1 shared Janis Veliks· 1 shared Laura PauninaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Aigars JirgensonsORCID

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1 paper

Recent·Most cited

Disassembly of the Escherichia coli AcrABZ-TolC efflux pump by ligand-mediated disruption of TolC-AcrA interfacial contacts

Tania Szal, Emmanouela Petsolari, Janis Veliks, Cristina D. Cruz, Laura Paunina, Marina Madre, Fatima-Zahra Rachad, Philipp Lewe, Susanne Witt, Päivi Tammela, Aigars Jirgensons, Ben F. Luisi, Björn Windshügel

The paper identifies a compound that disrupts the TolC-AcrA interface of the E. coli efflux pump, leading to pump disassembly and reduced antibiotic resistance.

bioRxiv · Feb 18, 2025 · PreprintMicrobiology