Author

Phillip Lazarus

Washington State University Spokane

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Bhagwat PrasadiD· 1 shared Dilip Kumar SinghiD· 1 shared Dmitri R. DavydoviD· 1 shared Kannapiran PonrajiD· 1 shared Kari A. GaitheriD· 1 shared Mengqi ZhaoiD· 1 shared Nadezhda Y. Davydova· 1 shared Shaman LuoiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Bhagwat PrasadORCID

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1 paper

Recent·Most cited

Non-additivity of the functional properties of individual P450 species and its manifestation in the effects of alcohol consumption on the metabolism of ketamine and amitriptyline

Kannapiran Ponraj, Kari A. Gaither, Dilip Kumar Singh, Nadezhda Y. Davydova, Mengqi Zhao, Shaman Luo, Phillip Lazarus, Bhagwat Prasad, Dmitri R. Davydov

The paper investigates how alcohol affects drug metabolism by analyzing interactions between P450 enzymes in human liver microsomes, finding alcohol increases low-affinity enzyme roles and alters enzyme-specific metabolic rates.

Biochemical Pharmacology · Jun 15, 2024Peer-reviewedBiochemistry