Author
Washington State University
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Dmitri R. Davydov, Kannapiran Ponraj, Nadezhda Y. Davydova…·Bhagwat Prasad
This study investigates how chronic alcohol exposure increases CYP3A enzyme activity in human liver microsomes through interactions with CYP2E1, despite no change in CYP3A levels.
Kari A. Gaither, Nadezhda Y. Davydova, Kannapiran Ponraj…·Dmitri R. Davydov
This paper introduces a new fluorogenic substrate, MONA, for CYP1A2 and uses it to study how chronic alcohol exposure affects CYP1A2 activity in human liver microsomes.
Kari A. Gaither, Dilip Kumar Singh, Guihua Yue…·Bhagwat Prasad
This study investigates how alcohol consumption and smoking affect drug-metabolizing enzymes and transporters in human liver microsomes, identifying significant changes in enzyme abundance and proposing an alcohol exposure index.
Kannapiran Ponraj, Kari A. Gaither, Dilip Kumar Singh…·Dmitri R. Davydov
The paper investigates how alcohol affects drug metabolism by analyzing interactions between P450 enzymes in human liver microsomes, finding alcohol increases low-affinity enzyme roles and alters enzyme-specific metabolic rates.