Stress decreases serotonin tone in the nucleus accumbens to promote aversion and potentiate cocaine preference via decreased stimulation of 5-HT1B receptors
Harrison M. Fontaine, Phillip R. Silva, Carlie Neiswanger, Rachelle Tran, Antony D. Abraham, Benjamin Bruce Land, John F. Neumaier, Charles Chavkin
The paper investigates how stress affects serotonin signaling in the nucleus accumbens through dynorphin and KOR pathways, influencing cocaine preference and aversion.
Neuropsychopharmacology · Sep 25, 2021Peer-reviewedNeuroscience