Carlie Neiswanger

The paper identifies brain-wide neural circuits activated by isoflurane anesthesia and shows chemogenetic manipulation of these circuits reproduces key aspects of unconsciousness.

The paper maps whole-brain neural activity during emergence from isoflurane anesthesia in mice and finds selective subcortical activation rather than global cortical reactivation.

This study identifies nalfurafine and nalmefene as agents that cause long-lasting KOR inactivation, potentially offering new therapeutic approaches for stress-related disorders.

This study identifies a brain-wide neural ensemble involved in anesthesia-induced unconsciousness, with the lateral parabrachial nucleus as a central hub.

This paper develops a fast, sensitive genetically encoded H2O2 sensor (oROS-G) and demonstrates its use in monitoring H2O2 dynamics in various cell types and models.

The paper investigates how stress affects serotonin signaling in the nucleus accumbens through dynorphin and KOR pathways, influencing cocaine preference and aversion.