BioengineeringMolecular TherapyPeer-reviewed
Evaluating the effects of aging on biodistribution and gene silencing activity of lipid-siRNA conjugates delivered into cerebrospinal fluid
Alexander P Ligocki, Alexander G. Sorets, Adam M Abdulrahman…·Ethan S. Lippmann
This study evaluates how aging affects the distribution and gene silencing activity of lipid-siRNA conjugates in the cerebrospinal fluid of mice.
DOI 10.1016/j.ymthe.2026.06.028